Moreover, negative pregnancy outcomes (stillbirths and prematurity) may be increased. For pregnant people more generally, the safety data allow us to be increasingly confident that the risks of vaccination are very small.”ĭaniele de Luca, MD, PhD, professor of neonatology at the Antoine Béclère Medical Center in France, agreed with Dr Male, stating “getting COVID-19 in pregnancy may lead to more severe forms and also to critical consequences needing ICU admission. Victoria Male, PhD, professor in the Department of Metabolism, Digestion, and Reproduction at Imperial College London, comments, “For pregnant women who are at high risk, either because they are highly exposed or because of existing health conditions, I think it’s clear that the benefits of vaccination outweigh the risks, and I certainly recommend vaccination in these groups.
What we’re left with is looking at the benefits of the vaccine versus the potential risks,” stated Sonja Rasmussen, MD, professor in the Departments of Pediatrics and Epidemiology at the University of Florida College of Medicine. “We don’t really know of any risks because pregnant women are oftentimes, for new medications and vaccines, excluded from the clinical trials. Given these potential risks, should pregnant or nursing women undergo vaccination? After birth, the infant tested positive for SARS-CoV-2 and exhibited bilateral gliosis in the brain at 11 days of life.
Immunohistochemical examination of placental tissue in a case study of a 23-year-old pregnant woman with COVID-19 revealed a very high placental viral load and markers of inflammation. In addition to complications with delivery, there is also some evidence that virus from an infected mother can reach the placenta. 1,5 The biological mechanism of this increased rate, whether it be a direct consequence of infection or some other factor brought on by the pandemic, has yet to be determined. During the pandemic, the rate of stillbirths has tripled to 9. Prior to the pandemic, stillbirths in the United Kingdom occurred at a rate of 2.
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